Ocular Defects in Still's Disease

A Case of Adult Onset Stills Disease

Adult-onset Still's disease (AOSD) is characterized by fever, rash, and joint pain and may lead to chronic arthritis. The cause of AOSD is unknown, and it is rare. We encountered a patient with adult-onset Still's disease following a sore throat and fever. The patient was a 40-year-old woman who consulted our hospital because of a sore throat, fever and arthritis. She was admitted and treated w...

Ocular Defects in Thalidomide Babies.

IN the early reports on congenital abnormalities in thalidomide babies in Great Britain little attention has been paid to the occurrence of ocular defects. A recent survey by the Chief Medical Officer of the Ministry of Health relating to children born with congenital limb deformities during 1960-62, revealed that there were 652 surviving children with such deformities, 244 of whose mothers had...

Ocular and vision defects in preschool children.

Ocular and/or vision defects are one of the commonest reasons for the referral of young children to hospital. In a survey of a birth cohort in one health district, 7.1% of children were diagnosed as having such defects by their fifth birthday; 2.1% were detected before the age of 2 years, and 5.1% between 2 and 5 years. Up to the age of 2 years, low birthweight children and those who require po...

Bilateral congenital ocular defects in a foal.

Lack of type XVIII collagen results in anterior ocular defects.

Mice lacking type XVIII collagen have defects in the posterior part of the eye, including delayed regression of the hyaloid vasculature and poor outgrowth of the retinal vessels. We report here that these mice also have a fragile iris and develop atrophy of the ciliary body. The irises of Col18a1-/- mice can be seen to adhere to the lens and cornea. After the pupils begin to function, the doubl...